Lepra tuberculoide. Rios González, Carlos Miguel Cátedra de Dermatología. Facultad de Ciencias Médicas. Universidad Nacional de Caaguazú. Paraguay. El 65,4 % de los casos índices fueron hombres y 22 (84,6 %) lepromatosos; dos tenían lepra indeterminada y dos tuberculoide. Los casos secundarios fueron. La lepra o malaltia de Hansen és una malaltia infectocontagiosa però difícilment . que estaran engruixits i es podran palpar, sobretot a la lepra tuberculoide.
|Published (Last):||25 July 2009|
|PDF File Size:||13.45 Mb|
|ePub File Size:||4.63 Mb|
|Price:||Free* [*Free Regsitration Required]|
Domiciliary care to be arranged for treating the ulcers. Although regarded as eradicated in Portugal, is still documented in neuropathological study of patients with clinical peripheral neuropathy without proper diagnosis. The reason for tuberculoixe different immune response of the two clinical forms remains unclear. The bilateral amaurosis and hypoacusia were noted.
Lepra lepromatosa: Revisión y caso clínico
At some undetermined point the patient suffers an initial bacillaemia, which may be repeated through recurrent episodes or progress toward a continuous bacteraemia. The antibodies produced by a given bacterial species may be capable of combining with membrane receptors of other species.
The nasal mucosa become ulcerated and form scabs. He is being monitored by his general practitioner and receives domiciliary care for his left knee lesions and diabetes. tuberculoidr
Hansen Neuropathy: Still a Possible Diagnosis in the Investigation of a Peripheral Neuropathy.
It is usually negative in lepromatous leprosy and positive in the tuberculoid form. Laboratory studies suggest there to be a defective T-cell response to the antigens of M. ,epra leprae, lepromatous leprosy, tuberculoid leprosy, differential diagnosis. Nevertheless, much remains to be known about the mechanism of interaction between the two diseases and further research is required.
Impact of leprosy on family and intimate relationships.
Studying by a new thecnics, which he baptised before as “Lleras’ method”, the scarching of the agent tuverculoide leprosy in tuberculoid cases, by examination of sub-corium lymph obtained from the lesion, he discovered new forms of the Hansen bacillus, which describes briefly, arriving at the following conclusions: None of the couples had had leprosy at the time of being married.
Cambridge University Press; Indian J Tuberrculoide Venereol Leprol ; Such bacteriological findigs and the proved mutation of tuberculoid leprosy into lepromatous type, demolished the basis of the so-called “polar” classification of leprosy.
Patient contact is the major determinant in incident leprosy: Diet to include carbohydrate monitoring and dietary supplements. As these bacteria multiply more in cooler areas the pattern of infection is usually focussed on the skin, superficial cutaneous structures especially peripheral nervesthe eyes and the testicles.
Discussion – Facial alterations: He also had problems swallowing and presented solid and liquid dysphagia. Certain complications, such as pyogenic infection with abscess formation and sepsis, may produce an abrupt and fatal change in the disease course. When the primary case was paucibacillary, no multibacillary leprosy occurred in the secondary case. Leprosy is still one of the most frequent causes of peripheral neuropathy. The most commonly used drugs are dapsone, rifampicin and clofazimine.
Int J Lepr other Mycobact Dis Atlas de enfermedades orales. Services on Demand Journal. Similares no Google Citados no Google Scholar. Ni los dimorfos ni los indeterminados presentaron discapacidad en las manos. In addition to these polar forms of immune response, a significant number of patients show a partial or incomplete response and present borderline forms of the disease.
Although the trunk may be affected, few lesions are generally observed in this region 1. Extended studies on the viability of Mycobacterium leprae outside the human body. Patients with lepromatous leprosy are highly infectious, although most exposed immunocompetent individuals do not contract the disease. Inthe WHO attempted to describe these degrees of semi-quantitative response, designating them as borderline tuberculoid BT and borderline lepromatous BL As few bacilli are found in the lesions of this clinical form it is known as paucibacillary.
Around one-third of people with leprosy present the first clinical manifestations during childhood. Depending on the stage at which they are diagnosed, the appearance of these lesions may be similar to those of other conditions and this makes the differential diagnosis difficult 2,6, Although both leprosy and tuberculosis were more common in the past they have never completely disappeared, as is illustrated by numerous publications throughout history.
El-orf, A, Stugh AM. The disease presents polar clinical forms the “multibacillary” lepromatous leprosy and the “paucibacillary” tuberculoid leprosyas well as other intermediate forms with hybrid characteristics Table 1. Our patient showed generalized changes in pigmentation, as can be seen in the figures.
In most nerve samples tuberculoid type of disease was identified. No paucibacillary cases were associated with multibacillary leprosy in the couples. They were aged from 20 to Quinolones, such as ofloxacin and pefloxacin, as well as some macrolides, such as clarithromycin and minocyclin, are also effective.
Dermatology Online Journal
The ulcers are slow to heal, and produce atrophic scarring or even tissue destruction. The Cambridge Encyclopedia of Human Paleopathology. Clinical aspects of leprosy. Once signs have appeared the disease will generally progress slowly unless treated. It is very rare for the reverse trend to be observed spontaneously, and it is only seen in treated patients 1. Time trends in the analysis of incidence rate of leprosy among household contacts.
The lesions are usually located on the hard and soft palate, in the uvula, on the underside of the tongue, and on the lips and gums. Leprosy situation in the world and multidrug therapy coverage. It is transmitted from person to person and has a long incubation period between two and six years.